期刊： KIDNEY INTERNATIONAL, 2023; 103 (2)
IgA nephropathy (IgAN) is the most common glomerulonephritis, characterized by the presence of predominant IgA deposits in the mesangium. Deposition o......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (4)
Glucagon-like peptide-1 receptor agonists reduce albuminuria and may stabilize the estimated glomerular filtration rate (eGFR) in people with type 2 d......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (4)
Activation of the renin-angiotensin system is associated with podocyte injury and has been well demonstrated as a pivotal factor in the progression of......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (5)
While patients receiving dialysis therapy in the United States are more likely to develop cardiovascular disease (CVD) than those in Japan, direct com......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (6)
Acute kidney injury (AKI) occurs in about half of critically ill patients and is associated with high in-hospital mortality, increased long-term morta......
期刊： KIDNEY INTERNATIONAL, 2023; 104 (1)
The role of parietal epithelial cells (PECs) in kidney function and disease was recently revisited. Building on previous studies of human kidney tissu......
期刊： KIDNEY INTERNATIONAL, 2023; 104 (1)
CD4(+) T cells that express forkhead box protein 3 are important in maintaining tolerance and restraining effector responses. Herrnstadt et al. use a ......
期刊： KIDNEY INTERNATIONAL, 2023; 104 (4)
Underlying molecular mechanisms of the kidney protective effects of sodium glucose co-transporter 2 (SGLT2) inhibitors are not fully elucidated. There......
期刊： KIDNEY INTERNATIONAL, 2023; 104 (5)
Matrix metalloproteinases (MMPs) cleave matrix components along with multiple other effects. They are integral to virtually all biological processes, ......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (1)
Children and youth with a congenital or acquired single functioning kidney are at risk for development of kidney injury and chronic kidney disease. Ho......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (1)
Autosomal dominant polycystic kidney disease (ADPKD) involves the development and persistent growth of fluid filled kidney cysts. In a recent study, w......
期刊： KIDNEY INTERNATIONAL, 2023; 103 (1)
Nedosiran is an investigational RNA interference agent designed to inhibit expression of hepatic lactate dehydrogenase, the enzyme thought responsible......
